Because the individual possesses a homozygous recessive genotype, albinism occurs in animals. A mutation in the tyrosinase gene, which creates the tyrosinase enzyme, can cause the albino phenotype in buffalo. Oculocutaneous albinism (albino in the eyes and skin) and ocular albinism are the two varieties of albinos (albino only in the eyes). Oculocutaneous albinism is the form of albinism that affects albino buffalo.